Introduction: Understanding GERD and the Role of PPIs
Gastroesophageal Reflux Disease (GERD) is a chronic and often progressive condition where stomach acid or bile flows into the esophagus, leading to symptoms such as heartburn, chest pain, regurgitation, and difficulty swallowing. If left untreated, it can lead to complications such as esophagitis, Barrett’s esophagus, or even esophageal cancer.
Proton Pump Inhibitors (PPIs) have revolutionized the treatment of GERD by providing highly effective and long-lasting acid suppression. By irreversibly inhibiting the H+/K+ ATPase enzyme system (proton pumps) in gastric parietal cells, PPIs significantly reduce acid secretion, giving the esophageal lining a chance to heal and relieving symptoms.
Rouzel is proud to present a comprehensive, scientifically developed PPI portfolio, designed to meet every clinical need — from standard acid suppression to complex cases involving motility disorders or vomiting.
Rouzel’s GERD Treatment Portfolio: Complete Product Breakdown
Dexlansoprazole Range
Dual Delayed-Release PPI for Extended Control
Dezom-60
Dexlansoprazole 60 mg Delayed-Release Capsules
➤ Unique dual-release formulation for prolonged acid suppression.
➤ Designed for once-daily dosing, even with nighttime symptoms.
➤ Ideal for patients with erosive esophagitis or persistent reflux.
Ilaprazole Combination for Functional Dyspepsia & GERD
Ilaroz-LS
Ilaprazole + Levosulpiride Sustained-Release Capsules
➤ Combines the acid suppression power of Ilaprazole, a newer PPI, with Levosulpiride, a prokinetic agent.
➤ Effective in GERD with gastric dysmotility, functional dyspepsia, and bloating.
➤ Reduces visceral hypersensitivity and improves quality of life.
Esomeprazole Range: Next-Generation Acid Control
Nexobel
Esomeprazole Gastro-Resistant Tablets
➤ Enhanced bioavailability and rapid onset of action.
➤ Effective for acid reflux, peptic ulcers, and H. pylori eradication regimens.
Nexobel-ES
Esomeprazole (EC) + Domperidone (SR) Capsules
➤ Offers superior acid control with prokinetic benefits.
➤ Domperidone reduces nausea, bloating, and accelerates gastric emptying.
➤ Excellent option for GERD with post-meal fullness or regurgitation.
Pediatric-Friendly Lansoprazole Formulation
Lanroz-Kid
Lansoprazole Orally Disintegrating Tablets (ODT)
➤ Specially designed for children and elderly patients.
➤ Easy-to-administer, disintegrates instantly on the tongue — no need for water.
➤ Effective in pediatric GERD, gastritis, and ulcer management.
Roupan Range: Pantoprazole-Based Therapy for Comprehensive GERD Management
Roupan-40
Pantoprazole Gastro-Resistant Tablets
➤ Trusted, effective treatment for acid-related disorders.
➤ Suitable for daily GERD management and prevention of NSAID-induced ulcers.
Roupan-D
Pantoprazole + Domperidone Tablets
➤ Combines acid suppression with antiemetic and gastric motility effects.
➤ Domperidone helps alleviate bloating, nausea, and reflux.
Roupan-DSR
Pantoprazole (EC) + Domperidone (SR) Capsules
➤ Dual-release technology ensures consistent relief throughout the day.
➤ Ideal for moderate to severe GERD and chronic dyspepsia.
Roupan-XL
Pantoprazole (EC) + Levosulpiride (SR) Capsules
➤ Levosulpiride enhances gastric and intestinal motility, making this product effective in refractory GERD and functional dyspepsia.
➤ Reduces gastric stasis and non-ulcer dyspepsia symptoms.
Roupan-IV
Pantoprazole for Injection
➤ For acute, hospitalized GERD cases, post-operative acid suppression, or patients unable to take oral therapy.
➤ Provides rapid and reliable acid control.
Roulet Range: Advanced Rabeprazole-Based Combinations
Roulet-20
Rabeprazole Tablets
➤ Known for its fast onset of action and potent acid suppression.
➤ Useful in GERD, Zollinger-Ellison syndrome, and peptic ulcers.
Roulet-O
Rabeprazole Sodium + Ondansetron Tablets
➤ Ideal for patients with acid reflux plus nausea or vomiting.
➤ Ondansetron provides powerful antiemetic action, useful in chemotherapy or gastritis.
Roulet-4G
Rabeprazole Sodium (EC) + Domperidone (SR) Capsules
➤ Dual-action formulation for day-long reflux control and improved GI motility.
Roulet-XL
Rabeprazole Sodium (EC) + Levosulpiride (SR) Capsules
➤ Comprehensive solution for GERD with functional gastrointestinal disorders like IBS-D.
Roulet-DSR
Rabeprazole Sodium (EC) + Domperidone (SR) Capsules
➤ Targets acid reflux, bloating, and nausea.
➤ SR coating ensures gradual, long-term symptom control.
Roulet-IV
Rabeprazole Injection
➤ Fast and effective intravenous acid suppression for ICU, post-surgery, or critical care settings.
Upraz Range: Classic Omeprazole-Based Solutions
Upraz-20
Omeprazole Capsules
➤ The original and time-tested PPI, proven effective in gastric ulcers and GERD.
➤ Ideal for cost-effective daily management of acid reflux.
Upraz-D
Omeprazole + Domperidone Capsules
➤ Combines classic acid suppression with gastric emptying and antiemetic support.
➤ Great for patients with nausea-predominant dyspepsia.
Why Rouzel? Science, Safety & Solutions
Rouzel’s extensive line of PPIs and combinations delivers:
✔️ Scientific Innovation: Modern EC and SR technology ensure superior absorption and efficacy.
✔️ Complete Spectrum: Monotherapies, dual therapies, and injectables.
✔️ Formulations for All Ages: ODTs for children, tablets and capsules for adults, injectables for emergencies.
✔️ Clinically Proven Molecules: Dexlansoprazole, Esomeprazole, Pantoprazole, Rabeprazole, Ilaprazole, Omeprazole.
✔️ Relief for Every Need: From simple acid reflux to GERD with motility or nausea components.
Conclusion: Rouzel – A Leader in Digestive Care
Whether you’re treating mild heartburn, managing chronic GERD, or addressing functional GI disorders, Rouzel offers a trusted, clinically optimized solution for every patient.
Backed by science. Built for relief.
Choose Rouzel — where expertise meets excellence in gastrointestinal care.
